Semaglutide is a drug analog of the hormone GLP-1, a hormone secreted in the intestine after meals and which confers satiety as well as regulating sugar metabolism. It is used with different dosages, indications and pharmacological form in the treatment of diabetes and obesity.

 

How does semaglutide work in the treatment of obesity?

Semaglutide works by reducing appetite and food cravings and increasing satiety, it also controls sugar metabolism.
Semaglutide has also been shown to prevent cardiovascular events.

 

How is semaglutide taken to treat obesity?

Semaglutide is taken by subcutaneous injection, once a week. The drug, compared to the hormone GLP-1 which has a half-life of 1-2 minutes, has a half-life of 165 hours. The full dose of 2.4 mg is reached gradually over time to avoid side effects of the medicine.

 

What are the side effects of semaglutide?

Side effects are mainly gastrointestinal: nausea, vomiting, diarrhea and constipation. Gallbladder stones may form in some people.

 

How much weight can you lose with semaglutide?

The average weight loss at 68 weeks in patients treated with semaglutide is approximately 15% of initial body weight.

 

Is Semaglutide approved in Italy for the treatment of obesity?

Semaglutide is currently approved in Italy only for the treatment of diabetes mellitus. AIFA is expected to approve obesity in 2023.

 

 

If you want to have more information, contact our aesthetic medical office in Rome.

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